Bioven mono bottle 25 ml
Description for Bioven MONO liquid 25 ml bottle:
DESCRIPTION: The drug is an immunologically active protein fraction isolated from human plasma, purified and concentrated by ethanol fractionation. Contains from 4.5 to 5.5% protein.
The drug has a low anticomplementary activity as a result of further purification of immunoglobulins produced by alcohol, from aggregated proteins and impurities. The active ingredient in are immunoglobulins possessing activity of antibodies of different specificity. The drug also has non-specific activity, which manifests itself in increasing resistance to infections.
INDICATIONS: Severe toxic forms of bacterial and viral infections, postoperative complications in children and adults, accompanied by septicemia; replacement therapy in primary and secondary immunodeficiencies.
APPLICATION: type in / drip. The rate of introduction for children should be between 0.08 to 0.5 ml / min depending on body weight for adults - 1-1.5 ml / min. More rapid administration may cause the development of collaptoid reaction.
In the treatment of bacterial and viral infections single dose of the drug in children should be 4.0 ml / kg (200 mg / kg). The drug is administered one or twice. In the treatment of bacterial and viral infections in adults a single dose of the drug should be 2.0 ml / kg (100 mg / kg) for 4 days.
In primary immunodeficiency patients with congenital agammaglobulinemia and hypogammaglobulinemia - from 4.0 to 6.0 ml / kg (200-300 mg / kg) of body weight. The course is repeated every 3-4 weeks.
In secondary immunodeficiency in patients with chronic lymphocytic leukemia - 4,0-10,0 ml / kg (200-500 mg / kg). The course is repeated every 3-4 weeks.
When idiopathic thrombocytopenic purpura drug administered at a dose of 8 ml / kg (400 mg / kg) for 5 consecutive days or appoint 20 ml / kg (1 g / kg) for 2 consecutive days. As clinically indicated the need to increase the number of platelets can be administered periodically maintenance dose.
Kawasaki syndrome drug administered at a dose of 20-40 ml / kg (1-2 g / kg) once as an adjunct to aspirin therapy.
If Guillain - Barre syndrome, chronic inflammatory demyelinating neuropathy - 0.4 g / kg for 5 days. If necessary, a 5-day course of treatment is repeated at intervals of 4 weeks.
The drug Biovit mono is used only in a hospital, subject to all rules of asepsis. Before the introduction of bottles kept at a temperature (20 ± 2) ° C for at least 2 hours and Muddy sediment containing p-ry application can not be.
After the injection vaccinated against measles and mumps is conducted not earlier than 3 months. After vaccination against these infections drug should be administered no earlier than 2 weeks, if necessary use Biovit mono earlier by a measles vaccine and mumps should be repeated. Vaccinations against other infections can be held in any period before or after drug administration.
CONTRAINDICATIONS immunoglobulin is contraindicated in persons with a history of severe allergic reactions to the introduction of protein drugs in human blood. Persons suffering from allergies or have a history of severe allergic diseases (asthma, atopic dermatitis, recurrent urticaria) on the background of administration of immunoglobulin and the next 8 days after treatment recommended to take an antihistamine. Persons suffering from immunopathological systemic diseases (immune diseases of the blood, connective tissue disease, nephritis, etc.) the drug is prescribed only after consultation with the appropriate specialist. In the period of acute allergic process, a drug made by the conclusion of an allergist for health reasons.
SIDE EFFECTS: response to immunoglobulin is usually absent. There may be chills, headache, nausea, vomiting, allergic reactions. In rare cases may develop local reactions in the form of redness, and fever up to 37,5 ° C for one night. In individuals with altered reactivity may develop allergic reactions of various types, in extremely rare cases - anaphylactic shock. In this regard, the person who received the drug should be kept under medical observation for 30 minutes. Room where the administration of the drug should be provided with antishock therapy.
SPECIAL INSTRUCTIONS: After the expiry date of drug use is unacceptable. The drug is not subject to perekontrolyu quality and prolong shelf life after it.
INTERACTION: drug therapy Biovit mono can be combined with other medicines.
Storage: at 2 to 10 ° C.