Volvit tablets 5mg №30
Description for Volvit tablets 5mg №30
Pharmacological properties: biotin (vitamin H, vitamin B7) is a water soluble B vitamins biotin in the body plays an important role in the metabolism of carbohydrates, fats and proteins, is essential for normal growth and development of cells. When ingested, biotin serves as coenzyme carboxylase, has insulin-like effect and is involved in the process of gluconeogenesis (glucokinase involved in the synthesis), so it helps to stabilize blood glucose, and improves the function of the nervous system. Biotin is a synergist of other B vitamins, folic acid, pantothenic acid, cyanocobalamin. There are data on the participation of biotin in the synthesis of purine nucleotides. Biotin is also a source of sulfur, which is involved in protein synthesis - collagen, and thus positively influences the structure of the skin and its appendages (hair, nails).
Biotin enters the human body from food, as well as synthesized intestinal microflora.
In the body, biotin is rapidly absorbed in the small intestine by passive diffusion, and then goes through the portal system in the liver and then - in the systemic circulation. The degree of binding of biotin to plasma proteins is 80%. The concentration of free biotin in the blood is usually 200-1200 mg / liter. Biotin penetrates the blood-brain barrier and placental barrier. The body is metabolized to form various metabolites. Derived biotin in the urine (6-50 mg / day) and faeces as unchanged (50%), as well as biologically inert metabolic products. The half-life depends on the amount of the administered dose and is about 26 hours after ingestion of a dose of 100 mg / kg body weight.
INDICATIONS: integrated management of diseases in adults and children over the age of 12 years due to lack of biotin: hair disease (increased delicacy and fragility of the hair, section hair loss, excessive oiliness or dryness of the hair, gray hair), skin diseases (dermatitis, oily seborrhea, dryness and peeling of the skin), nail disease (brittleness, delamination, dysplasia of nails and their structure), functional disorders of the gastrointestinal tract (including malabsorption syndrome), biotinidase deficiency, psycho-emotional disorders (irritability and fatigue, drowsiness, lethargy, muscle weakness) .
APPLICATION: The pill is taken orally Volvit before eating, drinking some water.
The recommended dose for the treatment of diseases of the nails, hair, skin and disorders of the nervous system is 5 mg of biotin per day.
Malabsorption syndrome recommended daily dose is 10 mg.
In children and adults with symptoms of biotin deficiency recommended daily dose is 5-20 mg.
When biotinidase deficiency in adults and children over the age of 12 years, the recommended dose is 5-10 mg / day.
Drug can be used for a long time, a continuous course of treatment is on average 1 month.
CONTRAINDICATIONS: Hypersensitivity to the drug. Age 12 years.
SIDE EFFECTS: allergic reactions if you are sensitive to biotin, which can occur with pain in the chest, shortness of breath, hives, skin rash.
Precautions: Pregnancy and breast-feeding. No data on use during pregnancy and lactation.
Ability to influence the reaction rate in the management of motor vehicles or other machines. No information about the negative influence of the drug on the speed of psychomotor reactions.
Children. Do not use the drug in children under the age of 12 years.
INTERACTIONS: The use of biotin with anticonvulsants may decrease the concentration of biotin in plasma by increasing its excretion in the urine. Valproic acid inhibits the activity of biotinidase, reducing the function of mitochondria in the liver. The protein contains raw egg protein avidin, which interacts with biotin, so you need to avoid their simultaneous use. Drinking large amounts of raw eggs for 2-3 weeks can cause a deficiency of biotin.
Pantothenic acid in high doses competes with biotin, so you need to avoid their simultaneous use.
OVERDOSE: reports on overdose of biotin does not.
STORAGE: in a dark place at temperatures above 25 ° C.